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RNA polymerase II depletion from the inactive X chromosome territory is not mediated by physical compartmentalization

Subnuclear compartmentalization has been proposed to play an important role in gene regulation by segregating active and inactive parts of the genome in distinct physical and biochemical environments. During X chromosome inactivation (XCI), the noncoding Xist RNA coats the X chromosome, triggers gen...

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Detalles Bibliográficos
Autores principales: Collombet, Samuel, Rall, Isabell, Dugast-Darzacq, Claire, Heckert, Alec, Halavatyi, Aliaksandr, Le Saux, Agnes, Dailey, Gina, Darzacq, Xavier, Heard, Edith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442225/
https://www.ncbi.nlm.nih.gov/pubmed/37291424
http://dx.doi.org/10.1038/s41594-023-01008-5