RNA stability controlled by m(6)A methylation contributes to X-to-autosome dosage compensation in mammals

In mammals, X-chromosomal genes are expressed from a single copy since males (XY) possess a single X chromosome, while females (XX) undergo X inactivation. To compensate for this reduction in dosage compared with two active copies of autosomes, it has been proposed that genes from the active X chrom...

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Detalles Bibliográficos
Autores principales: Rücklé, Cornelia, Körtel, Nadine, Basilicata, M. Felicia, Busch, Anke, Zhou, You, Hoch-Kraft, Peter, Tretow, Kerstin, Kielisch, Fridolin, Bertin, Marco, Pradhan, Mihika, Musheev, Michael, Schweiger, Susann, Niehrs, Christof, Rausch, Oliver, Zarnack, Kathi, Keller Valsecchi, Claudia Isabelle, König, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442230/
https://www.ncbi.nlm.nih.gov/pubmed/37202476
http://dx.doi.org/10.1038/s41594-023-00997-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442230/
https://www.ncbi.nlm.nih.gov/pubmed/37202476
http://dx.doi.org/10.1038/s41594-023-00997-7

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