Cargando…
RNA stability controlled by m(6)A methylation contributes to X-to-autosome dosage compensation in mammals
In mammals, X-chromosomal genes are expressed from a single copy since males (XY) possess a single X chromosome, while females (XX) undergo X inactivation. To compensate for this reduction in dosage compared with two active copies of autosomes, it has been proposed that genes from the active X chrom...
| Autores principales: | , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group US
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442230/ https://www.ncbi.nlm.nih.gov/pubmed/37202476 http://dx.doi.org/10.1038/s41594-023-00997-7 |