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Erythropoietin re-wires cognition-associated transcriptional networks

Recombinant human erythropoietin (rhEPO) has potent procognitive effects, likely hematopoiesis-independent, but underlying mechanisms and physiological role of brain-expressed EPO remained obscure. Here, we provide transcriptional hippocampal profiling of male mice treated with rhEPO. Based on ~108,...

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Detalles Bibliográficos
Autores principales: Singh, Manvendra, Zhao, Ying, Gastaldi, Vinicius Daguano, Wojcik, Sonja M., Curto, Yasmina, Kawaguchi, Riki, Merino, Ricardo M., Garcia-Agudo, Laura Fernandez, Taschenberger, Holger, Brose, Nils, Geschwind, Daniel, Nave, Klaus-Armin, Ehrenreich, Hannelore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442354/
https://www.ncbi.nlm.nih.gov/pubmed/37604818
http://dx.doi.org/10.1038/s41467-023-40332-8