Pancreatic acinar cell fate relies on system x(C)(-) to prevent ferroptosis during stress

Acinar cell dedifferentiation is one of the most notable features of acute and chronic pancreatitis. It can also be the initial step that facilitates pancreatic cancer development. In the present study, we further decipher the precise mechanisms and regulation using primary human cells and murine ex...

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Detalles Bibliográficos
Autores principales: Pan, Zhaolong, Van den Bossche, Jan-Lars, Rodriguez-Aznar, Eva, Janssen, Pauline, Lara, Olaya, Ates, Gamze, Massie, Ann, De Paep, Diedert Luc, Houbracken, Isabelle, Mambretti, Marco, Rooman, Ilse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442358/
https://www.ncbi.nlm.nih.gov/pubmed/37604805
http://dx.doi.org/10.1038/s41419-023-06063-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442358/
https://www.ncbi.nlm.nih.gov/pubmed/37604805
http://dx.doi.org/10.1038/s41419-023-06063-w

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