Redox driven B(12)-ligand switch drives CarH photoresponse

CarH is a coenzyme B(12)-dependent photoreceptor involved in regulating carotenoid biosynthesis. How light-triggered cleavage of the B(12) Co-C bond culminates in CarH tetramer dissociation to initiate transcription remains unclear. Here, a series of crystal structures of the CarH B(12)-binding doma...

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Detalles Bibliográficos
Autores principales: Poddar, Harshwardhan, Rios-Santacruz, Ronald, Heyes, Derren J., Shanmugam, Muralidharan, Brookfield, Adam, Johannissen, Linus O., Levy, Colin W., Jeffreys, Laura N., Zhang, Shaowei, Sakuma, Michiyo, Colletier, Jacques-Philippe, Hay, Sam, Schirò, Giorgio, Weik, Martin, Scrutton, Nigel S., Leys, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442372/
https://www.ncbi.nlm.nih.gov/pubmed/37604813
http://dx.doi.org/10.1038/s41467-023-40817-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442372/
https://www.ncbi.nlm.nih.gov/pubmed/37604813
http://dx.doi.org/10.1038/s41467-023-40817-6

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