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Vacuolar-ATPase-mediated muscle acidification caused muscular mechanical nociceptive hypersensitivity after chronic stress in rats, which involved extracellular matrix proteoglycan and ASIC3

Although widespread pain, such as fibromyalgia, is considered to have a central cause, peripheral input is important. We used a rat repeated cold stress (RCS) model with many characteristics common to fibromyalgia and studied the possible involvement of decreased muscle pH in muscle mechanical hyper...

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Detalles Bibliográficos
Autores principales: Nasu, Teruaki, Hori, Amane, Hotta, Norio, Kihara, Chiaki, Kubo, Asako, Katanosaka, Kimiaki, Suzuki, Masamitsu, Mizumura, Kazue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442418/
https://www.ncbi.nlm.nih.gov/pubmed/37604935
http://dx.doi.org/10.1038/s41598-023-39633-1