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Vacuolar-ATPase-mediated muscle acidification caused muscular mechanical nociceptive hypersensitivity after chronic stress in rats, which involved extracellular matrix proteoglycan and ASIC3
Although widespread pain, such as fibromyalgia, is considered to have a central cause, peripheral input is important. We used a rat repeated cold stress (RCS) model with many characteristics common to fibromyalgia and studied the possible involvement of decreased muscle pH in muscle mechanical hyper...
Autores principales: | Nasu, Teruaki, Hori, Amane, Hotta, Norio, Kihara, Chiaki, Kubo, Asako, Katanosaka, Kimiaki, Suzuki, Masamitsu, Mizumura, Kazue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442418/ https://www.ncbi.nlm.nih.gov/pubmed/37604935 http://dx.doi.org/10.1038/s41598-023-39633-1 |
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