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Roles unveiled for membrane-associated mucins at the ocular surface using a Muc4 knockout mouse model

Membrane-associated mucins (MAMs) are proposed to play critical roles at the ocular surface; however, in vivo evidence has been lacking. Here we investigate these roles by phenotyping of a Muc4 KO mouse. Histochemical analysis for expression of the beta-galactosidase transgene replacing Muc4 reveale...

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Detalles Bibliográficos
Autores principales: Martinez-Carrasco, Rafael, Rachagani, Satyanarayan, Batra, Surinder K., Argüeso, Pablo, Fini, M. Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442421/
https://www.ncbi.nlm.nih.gov/pubmed/37604830
http://dx.doi.org/10.1038/s41598-023-40491-0