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Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC

Clear cell renal cell carcinoma (ccRCC) is the most common subtype of kidney cancer and is associated with poor prognosis. The histone H3 lysine 36 methyltransferase SET-domain-containing 2 (SETD2) has been reported to be expressed at low levels and frequently mutated in ccRCC. Ferroptosis, a form o...

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Detalles Bibliográficos
Autores principales: Xue, Wei, Jian, Wengang, Meng, Yuyang, Wang, Tengda, Cai, Licheng, Yu, Yongchun, Yu, Yipeng, Xia, Zhinan, Zhang, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442429/
https://www.ncbi.nlm.nih.gov/pubmed/37604811
http://dx.doi.org/10.1038/s41419-023-06057-8