Yeast lacking the sterol C-5 desaturase Erg3 are tolerant to the anti-inflammatory triterpenoid saponin escin

Escin is a mixture of over 30 glycosylated triterpenoid (saponin) structures, extracted from the dried fruit of horse chestnuts. Escin is currently used as an anti-inflammatory, and has potential applications in the treatment of arthritis and cancer. Engineered yeast would enable production of speci...

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Detalles Bibliográficos
Autores principales: Johnston, Emily J., Tallis, Jess, Cunningham-Oakes, Edward, Moses, Tessa, Moore, Simon J., Hosking, Sarah, Rosser, Susan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442444/
https://www.ncbi.nlm.nih.gov/pubmed/37604855
http://dx.doi.org/10.1038/s41598-023-40308-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442444/
https://www.ncbi.nlm.nih.gov/pubmed/37604855
http://dx.doi.org/10.1038/s41598-023-40308-0

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