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Yeast lacking the sterol C-5 desaturase Erg3 are tolerant to the anti-inflammatory triterpenoid saponin escin
Escin is a mixture of over 30 glycosylated triterpenoid (saponin) structures, extracted from the dried fruit of horse chestnuts. Escin is currently used as an anti-inflammatory, and has potential applications in the treatment of arthritis and cancer. Engineered yeast would enable production of speci...
Autores principales: | Johnston, Emily J., Tallis, Jess, Cunningham-Oakes, Edward, Moses, Tessa, Moore, Simon J., Hosking, Sarah, Rosser, Susan J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442444/ https://www.ncbi.nlm.nih.gov/pubmed/37604855 http://dx.doi.org/10.1038/s41598-023-40308-0 |
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