Multiple LDLR class A repeats on very‐low‐density lipoprotein receptor promote the cross‐species transmission of Semliki Forest virus

Multiple LDLR class A (LA) repeats around LA3 promote synergistic binding to Semliki Forest virus (SFV) E1‐DIII near the 2‐fold and 5‐fold symmetry axes. Meanwhile, the multiple consecutive LAs concatemer shows approximately 1000 times higher binding affinity than that of LA3s, which can help to eff...

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Detalles Bibliográficos
Autores principales: Hu, Ruolan, Li, Maochen, Fan, Huahao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Highlights
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442473/
https://www.ncbi.nlm.nih.gov/pubmed/37614966
http://dx.doi.org/10.1002/mco2.351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442473/
https://www.ncbi.nlm.nih.gov/pubmed/37614966
http://dx.doi.org/10.1002/mco2.351

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