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Role of Ceramide Synthase 1 in Oral Leukoplakia and Oral Squamous Cell Carcinoma: A Potential Linchpin for Tumorigenesis

Background Ceramide (CER), known as a "tumor suppressor lipid," plays a crucial role in promoting apoptosis in cancer cells. Ceramide synthase 1 (CERS1), an enzyme responsible for CER synthesis, holds immense importance. Notably, studies have highlighted that reduced levels of CERS1 confer...

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Detalles Bibliográficos
Autores principales: Surendran, Sangamithra, Poothakulath Krishnan, Reshma, Ramani, Pratibha, Ramalingam, Karthikeyan, Jayaraman, Selvaraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442516/
https://www.ncbi.nlm.nih.gov/pubmed/37614280
http://dx.doi.org/10.7759/cureus.42308