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Knockdown of the TRPM4 channel alters cardiac electrophysiology and hemodynamics in a sex‐ and age‐dependent manner in mice

TRPM4 is a calcium‐activated, voltage‐modulated, nonselective ion channel widely expressed in various cells and tissues. TRPM4 regulates the influx of sodium ions, thus playing a role in regulating the membrane potential. In the heart, TRPM4 is expressed in both cardiomyocytes and cells of the condu...

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Detalles Bibliográficos
Autores principales: Arullampalam, Prakash, Essers, Maria C., Boukenna, Mey, Guichard, Sabrina, Rougier, Jean‐Sébastien, Abriel, Hugues
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442522/
https://www.ncbi.nlm.nih.gov/pubmed/37604672
http://dx.doi.org/10.14814/phy2.15783