An efficient method to access spiro pseudoindoxyl ketones: evaluation of indoxyl and their N-benzylated derivatives for inhibition of the activity of monoamine oxidases

A simple, metal-free approach was developed to obtain novel pseudoindoxyl derivatives. The reaction was mediated by tBuOK on tetrahydrocarbazole 8 in dimethyl sulfoxide (DMSO) at room temperature through the hydroxylation of the indole double bond and a subsequent pinacol-type rearrangement. Spiro p...

Descripción completa

Detalles Bibliográficos
Autores principales: Perumal, Karuppaiah, Lee, Jiseong, Annes, Sesuraj Babiola, Ramesh, Subburethinam, Rangarajan, T. M., Mathew, Bijo, Kim, Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442599/
https://www.ncbi.nlm.nih.gov/pubmed/37614797
http://dx.doi.org/10.1039/d3ra03641c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442599/
https://www.ncbi.nlm.nih.gov/pubmed/37614797
http://dx.doi.org/10.1039/d3ra03641c

Ejemplares similares