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An efficient method to access spiro pseudoindoxyl ketones: evaluation of indoxyl and their N-benzylated derivatives for inhibition of the activity of monoamine oxidases

A simple, metal-free approach was developed to obtain novel pseudoindoxyl derivatives. The reaction was mediated by tBuOK on tetrahydrocarbazole 8 in dimethyl sulfoxide (DMSO) at room temperature through the hydroxylation of the indole double bond and a subsequent pinacol-type rearrangement. Spiro p...

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Detalles Bibliográficos
Autores principales:	Perumal, Karuppaiah, Lee, Jiseong, Annes, Sesuraj Babiola, Ramesh, Subburethinam, Rangarajan, T. M., Mathew, Bijo, Kim, Hoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442599/ https://www.ncbi.nlm.nih.gov/pubmed/37614797 http://dx.doi.org/10.1039/d3ra03641c

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