Substrate-specific binding of 8-oxoguanine DNA glycosylase 1 (OGG1) reprograms mucosal adaptations to chronic airway injury

Recent advances have uncovered the non-random distribution of 7, 8-dihydro-8-oxoguanine (8-oxoGua) induced by reactive oxygen species, which is believed to have epigenetic effects. Its cognate repair protein, 8-oxoguanine DNA glycosylase 1 (OGG1), reads oxidative substrates and participates in trans...

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Detalles Bibliográficos
Autores principales: Pan, Lang, Vlahopoulos, Spiros, Tanner, Lloyd, Bergwik, Jesper, Bacsi, Attila, Radak, Zsolt, Egesten, Arne, Ba, Xueqing, Brasier, Allan R., Boldogh, Istvan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442650/
https://www.ncbi.nlm.nih.gov/pubmed/37614238
http://dx.doi.org/10.3389/fimmu.2023.1186369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442650/
https://www.ncbi.nlm.nih.gov/pubmed/37614238
http://dx.doi.org/10.3389/fimmu.2023.1186369

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