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Substrate-specific binding of 8-oxoguanine DNA glycosylase 1 (OGG1) reprograms mucosal adaptations to chronic airway injury
Recent advances have uncovered the non-random distribution of 7, 8-dihydro-8-oxoguanine (8-oxoGua) induced by reactive oxygen species, which is believed to have epigenetic effects. Its cognate repair protein, 8-oxoguanine DNA glycosylase 1 (OGG1), reads oxidative substrates and participates in trans...
Autores principales: | Pan, Lang, Vlahopoulos, Spiros, Tanner, Lloyd, Bergwik, Jesper, Bacsi, Attila, Radak, Zsolt, Egesten, Arne, Ba, Xueqing, Brasier, Allan R., Boldogh, Istvan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442650/ https://www.ncbi.nlm.nih.gov/pubmed/37614238 http://dx.doi.org/10.3389/fimmu.2023.1186369 |
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