Synthesis of amantadine clubbed N-aryl amino thiazoles as potent urease, α-amylase & α-glucosidase inhibitors, kinetic and molecular docking studies

A series of ten novel compounds were synthesized by incorporating a 1,3 thiazole core into amantadine and their structures were validated using different analytical and spectral methods such as FTIR, EI-MS, (1)H NMR, and (13)C NMR. The antibacterial and enzyme inhibitory properties of these newly sy...

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Detalles Bibliográficos
Autores principales: Zahra, Fatima Tuz, Saeed, Aamer, Ahmed, Atteeque, Ismail, Hammad, Ijaz, Muhammad Umar, Albericio, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442672/
https://www.ncbi.nlm.nih.gov/pubmed/37614781
http://dx.doi.org/10.1039/d3ra05330j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442672/
https://www.ncbi.nlm.nih.gov/pubmed/37614781
http://dx.doi.org/10.1039/d3ra05330j

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