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Synthesis of amantadine clubbed N-aryl amino thiazoles as potent urease, α-amylase & α-glucosidase inhibitors, kinetic and molecular docking studies
A series of ten novel compounds were synthesized by incorporating a 1,3 thiazole core into amantadine and their structures were validated using different analytical and spectral methods such as FTIR, EI-MS, (1)H NMR, and (13)C NMR. The antibacterial and enzyme inhibitory properties of these newly sy...
Autores principales: | Zahra, Fatima Tuz, Saeed, Aamer, Ahmed, Atteeque, Ismail, Hammad, Ijaz, Muhammad Umar, Albericio, Fernando |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442672/ https://www.ncbi.nlm.nih.gov/pubmed/37614781 http://dx.doi.org/10.1039/d3ra05330j |
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