Fine-tuning the cytotoxicity of ruthenium(ii) arene compounds to enhance selectivity against breast cancers

Ruthenium-based complexes have been suggested as promising anticancer drugs exhibiting reduced general toxicity compared to platinum-based drugs. In particular, Ru(η(6)-arene)(PTA)Cl(2) (PTA = 1,3,5-triaza-7-phosphaadamantane), or RAPTA, complexes have demonstrated efficacy against breast cancer by...

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Detalles Bibliográficos
Autores principales: Pereira, Sarah A. P., Romano-deGea, Jan, Barbosa, Ana Isabel, Costa Lima, Sofia A., Dyson, Paul J., Saraiva, M. Lúcia M. F. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442743/
https://www.ncbi.nlm.nih.gov/pubmed/37552495
http://dx.doi.org/10.1039/d3dt02037a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442743/
https://www.ncbi.nlm.nih.gov/pubmed/37552495
http://dx.doi.org/10.1039/d3dt02037a

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