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Toll-like receptor 4 and Syk kinase shape dendritic cell-induced immune activation to major house dust mite allergens

BACKGROUND: House dust mite (HDM) is a major cause of respiratory allergic diseases. Dendritic cells (DCs) play a central role in orchestrating adaptive allergic immune responses. However, it remains unclear how DCs become activated by HDM. Biochemical functions of the major HDM allergens Der p 1 (c...

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Detalles Bibliográficos
Autores principales: Busold, Stefanie, Akkerdaas, Jaap H., Zijlstra-Willems, Esther M., van der Graaf, Kees, Tas, Sander W., de Jong, Esther C., van Ree, Ronald, Geijtenbeek, Teunis B. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442820/
https://www.ncbi.nlm.nih.gov/pubmed/37614946
http://dx.doi.org/10.3389/fmed.2023.1105538