HSP27 Inhibitory Activity against Caspase-3 Cleavage and Activation by Caspase-9 Is Enhanced by Chaperone O-GlcNAc Modification in Vitro

[Image: see text] One of the O-GlcNAc modifications is the protection of cells against a variety of stressors that result in cell death. Previous experiments have focused on the overall ability of O-GlcNAc to prevent protein aggregation under stress as well as its ability to affect stress-response s...

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Detalles Bibliográficos
Autores principales: Wang, Binyou, Moon, Stuart P., Cutolo, Giuliano, Javed, Afraah, Ahn, Benjamin S., Ryu, Andrew H., Pratt, Matthew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442853/
https://www.ncbi.nlm.nih.gov/pubmed/37450938
http://dx.doi.org/10.1021/acschembio.3c00270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442853/
https://www.ncbi.nlm.nih.gov/pubmed/37450938
http://dx.doi.org/10.1021/acschembio.3c00270

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