Tumor necrosis factor mediates USE1-independent FAT10ylation under inflammatory conditions

The ubiquitin-like modifier FAT10 is up-regulated in many different cell types by IFNγ and TNFα (TNF) and directly targets proteins for proteasomal degradation. FAT10 gets covalently conjugated to its conjugation substrates by the E1 activating enzyme UBA6, the E2 conjugating enzyme USE1, and E3 lig...

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Detalles Bibliográficos
Autores principales: Schnell, Leonie, Zubrod, Alina, Catone, Nicola, Bialas, Johanna, Aichem, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442930/
https://www.ncbi.nlm.nih.gov/pubmed/37604583
http://dx.doi.org/10.26508/lsa.202301985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442930/
https://www.ncbi.nlm.nih.gov/pubmed/37604583
http://dx.doi.org/10.26508/lsa.202301985

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