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Loss of NSUN6 inhibits osteosarcoma progression by downregulating EEF1A2 expression and activation of Akt/mTOR signaling pathway via m(5)C methylation

As an important 5-methylcytidine (m(5)C) methyltransferase, NOP2/Sun RNA methyltransferase family member 6 (NSUN6) has been reported to play an important role in the progression of several diseases. However, the role of NSUN6 in the progression of osteosarcoma (OS) remains unclear. This study aimed...

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Detalles Bibliográficos
Autores principales: Hu, Sang, Yang, Min, Xiao, Kangwen, Yang, Zhiqiang, Cai, Lin, Xie, Yuanlong, Wang, Linlong, Wei, Renxiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10443047/
https://www.ncbi.nlm.nih.gov/pubmed/37614424
http://dx.doi.org/10.3892/etm.2023.12156