The nuclear Argonaute HRDE-1 directs target gene re-localization and shuttles to nuage to promote small RNA-mediated inherited silencing

Argonaute/small RNA pathways and heterochromatin work together to propagate transgenerational gene silencing, but the mechanisms behind their interaction are not well understood. Here, we show that induction of heterochromatin silencing in C. elegans by RNAi or by artificially tethering pathway comp...

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Detalles Bibliográficos
Autores principales: Ding, Yue-He, Ochoa, Humberto J., Ishidate, Takao, Shirayama, Masaki, Mello, Craig C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10443184/
https://www.ncbi.nlm.nih.gov/pubmed/37083324
http://dx.doi.org/10.1016/j.celrep.2023.112408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10443184/
https://www.ncbi.nlm.nih.gov/pubmed/37083324
http://dx.doi.org/10.1016/j.celrep.2023.112408

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