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Exploring Parametric and Mechanistic Differences between Expi293F(TM) and ExpiCHO-S(TM) Cells for Transient Antibody Production Optimization

Rapidly producing drug-like antibody therapeutics for lead molecule discovery and candidate optimization is typically accomplished by large-scale transient gene expression technologies (TGE) with cultivated mammalian cells. The TGE methodologies have been extensively developed over the past three de...

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Detalles Bibliográficos
Autores principales: Zhou, Jing, Yan, Guoying Grace, Cluckey, David, Meade, Caryl, Ruth, Margaret, Sorm, Rhady, Tam, Amy S., Lim, Sean, Petridis, Constantine, Lin, Laura, D’Antona, Aaron M., Zhong, Xiaotian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10443273/
https://www.ncbi.nlm.nih.gov/pubmed/37606437
http://dx.doi.org/10.3390/antib12030053