YAP Inactivation by Soft Mechanotransduction Relieves MAFG for Tumor Cell Dedifferentiation

Solid tumor cells live in a highly dynamic mechanical microenvironment. How the extracellular-matrix-generated mechanotransduction regulates tumor cell development and differentiation remains an enigma. Here, we show that a low mechanical force generated from the soft matrix induces dedifferentiatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Lv, Jiadi, Liu, Xiaohan, Zhou, Yabo, Cheng, Feiran, Chen, Haoran, Li, Shunshun, Wang, Dianheng, Zhou, Li, Wang, Zhenfeng, Zhou, Nannan, Chen, Jie, Huang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAAS 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10443527/
https://www.ncbi.nlm.nih.gov/pubmed/37614365
http://dx.doi.org/10.34133/research.0215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10443527/
https://www.ncbi.nlm.nih.gov/pubmed/37614365
http://dx.doi.org/10.34133/research.0215

Ejemplares similares