Spatial transcriptomics for profiling the tropism of viral vectors in tissues

A barrier to advancing engineered adeno-associated viral vectors (AAVs) for precision access to cell subtypes is a lack of high-throughput, high-resolution assays to characterize in vivo transduction profiles. In this study, we developed an ultrasensitive, sequential fluorescence in situ hybridizati...

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Detalles Bibliográficos
Autores principales: Jang, Min J., Coughlin, Gerard M., Jackson, Cameron R., Chen, Xinhong, Chuapoco, Miguel R., Vendemiatti, Julia L., Wang, Alexander Z., Gradinaru, Viviana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10443732/
https://www.ncbi.nlm.nih.gov/pubmed/36702899
http://dx.doi.org/10.1038/s41587-022-01648-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10443732/
https://www.ncbi.nlm.nih.gov/pubmed/36702899
http://dx.doi.org/10.1038/s41587-022-01648-w

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