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Astragaloside IV relieves IL-1β-induced human nucleus pulposus cells degeneration through modulating PI3K/Akt signaling pathway

BACKGROUND: Intervertebral disc degeneration (IDD) is a multifactorial disease that is associated with nucleus pulposus (NP) apoptosis and extracellular matrix (ECM) degeneration and inflammation. Astragaloside IV (AS IV) has antioxidant, free radical scavenging, anti-inflammatory and anti-apoptosis...

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Detalles Bibliográficos
Autores principales: Zhang, Lu, Gao, Junsheng, Li, Zhentao, Liu, Jun, Zhang, Chong, Liu, Jie, Dong, Hui, Mei, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10443759/
https://www.ncbi.nlm.nih.gov/pubmed/37603510
http://dx.doi.org/10.1097/MD.0000000000034815