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Astragaloside IV relieves IL-1β-induced human nucleus pulposus cells degeneration through modulating PI3K/Akt signaling pathway

BACKGROUND: Intervertebral disc degeneration (IDD) is a multifactorial disease that is associated with nucleus pulposus (NP) apoptosis and extracellular matrix (ECM) degeneration and inflammation. Astragaloside IV (AS IV) has antioxidant, free radical scavenging, anti-inflammatory and anti-apoptosis...

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Detalles Bibliográficos
Autores principales:	Zhang, Lu, Gao, Junsheng, Li, Zhentao, Liu, Jun, Zhang, Chong, Liu, Jie, Dong, Hui, Mei, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2023
Materias:	4200
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10443759/ https://www.ncbi.nlm.nih.gov/pubmed/37603510 http://dx.doi.org/10.1097/MD.0000000000034815

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