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Individual transcriptomic response to strength training for patients with myotonic dystrophy type 1

Myotonic dystrophy type 1 (DM1), the most common form of adult-onset muscular dystrophy, is caused by a CTG expansion resulting in significant transcriptomic dysregulation that leads to muscle weakness and wasting. While strength training is clinically beneficial in DM1, molecular effects had not be...

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Detalles Bibliográficos
Autores principales: Davey, Emily E., Légaré, Cécilia, Planco, Lori, Shaughnessy, Sharon, Lennon, Claudia D., Roussel, Marie-Pier, Shorrock, Hannah K., Hung, Man, Cleary, John Douglas, Duchesne, Elise, Berglund, J. Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10443797/
https://www.ncbi.nlm.nih.gov/pubmed/37318869
http://dx.doi.org/10.1172/jci.insight.163856