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Early ART reduces viral seeding and innate immunity in liver and lungs of SIV-infected macaques

Identifying immune cells and anatomical tissues that contribute to the establishment of viral reservoirs is of central importance in HIV-1 cure research. Herein, we used rhesus macaques (RMs) infected with SIVmac251 to analyze viral seeding in the liver and lungs of either untreated or early antiret...

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Detalles Bibliográficos
Autores principales: Clain, Julien A., Rabezanahary, Henintsoa, Racine, Gina, Boutrais, Steven, Soundaramourty, Calaiselvy, Joly Beauparlant, Charles, Jenabian, Mohammad-Ali, Droit, Arnaud, Ancuta, Petronela, Zghidi-Abouzid, Ouafa, Estaquier, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10443800/
https://www.ncbi.nlm.nih.gov/pubmed/37485876
http://dx.doi.org/10.1172/jci.insight.167856