Targeting a xenobiotic transporter to ameliorate vincristine-induced sensory neuropathy

Vincristine is a widely used chemotherapeutic drug for the treatment of multiple malignant diseases that causes a dose-limiting peripheral neurotoxicity. There is no clinically effective preventative treatment for vincristine-induced sensory peripheral neurotoxicity (VIPN), and mechanistic details o...

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Detalles Bibliográficos
Autores principales: Li, Yang, Drabison, Thomas, Nepal, Mahesh, Ho, Richard H., Leblanc, Alix F., Gibson, Alice A., Jin, Yan, Yang, Wenjian, Huang, Kevin M., Uddin, Muhammad Erfan, Chen, Mingqing, DiGiacomo, Duncan F., Chen, Xihui, Razzaq, Sobia, Tonniges, Jeffrey R., McTigue, Dana M., Mims, Alice S., Lustberg, Maryam B., Wang, Yijia, Hummon, Amanda B., Evans, William E., Baker, Sharyn D., Cavaletti, Guido, Sparreboom, Alex, Hu, Shuiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10443802/
https://www.ncbi.nlm.nih.gov/pubmed/37347545
http://dx.doi.org/10.1172/jci.insight.164646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10443802/
https://www.ncbi.nlm.nih.gov/pubmed/37347545
http://dx.doi.org/10.1172/jci.insight.164646

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