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Leishmania major drives host phagocyte death and cell-to-cell transfer depending on intracellular pathogen proliferation rate

The virulence of intracellular pathogens relies largely on the ability to survive and replicate within phagocytes but also on release and transfer into new host cells. Such cell-to-cell transfer could represent a target for counteracting microbial pathogenesis. However, our understanding of the unde...

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Detalles Bibliográficos
Autores principales: Baars, Iris, Jaedtka, Moritz, Dewitz, Leon-Alexander, Fu, Yan, Franz, Tobias, Mohr, Juliane, Gintschel, Patricia, Berlin, Hannes, Degen, Angelina, Freier, Sandra, Rygol, Stefan, Schraven, Burkhart, Kahlfuß, Sascha, van Zandbergen, Ger, Müller, Andreas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10443809/
https://www.ncbi.nlm.nih.gov/pubmed/37310793
http://dx.doi.org/10.1172/jci.insight.169020