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Metabolomics identifies disturbances in arginine, phenylalanine, and glycine metabolism as differentiating features of exacerbating atopic asthma in children

BACKGROUND: Asthma exacerbations are highly prevalent in children, but only a few studies have examined the biologic mechanisms underlying exacerbations in this population. OBJECTIVE: High-resolution metabolomics analyses were performed to understand the differences in metabolites in children with e...

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Detalles Bibliográficos
Autores principales: Cottrill, Kirsten A., Chandler, Joshua D., Kobara, Seibi, Stephenson, Susan T., Mohammad, Ahmad F., Tidwell, Mallory, Mason, Carrie, Van Dresser, Morgan, Patrignani, James, Kamaleswaran, Rishikesan, Fitzpatrick, Anne M., Grunwell, Jocelyn R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10443927/
https://www.ncbi.nlm.nih.gov/pubmed/37609569
http://dx.doi.org/10.1016/j.jacig.2023.100115