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Icariin restrains NLRP3 inflammasome-mediated Th2 immune responses and ameliorates atopic dermatitis through modulating a novel lncRNA MALAT1/miR-124-3p axis

CONTEXT: Atopic dermatitis (AD) is a common inflammatory skin disease characterized with hyperactivation of type 2 T helper (Th2) immune responses. Icariin is a flavonoid glucoside with anti-inflammatory activities, which has been used to treat multiple diseases. OBJECTIVE: The present study investi...

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Detalles Bibliográficos
Autores principales: Zhao, Wei, Yu, Huan-Huan, Meng, Wei-Wei, Liu, Ai-Min, Zhang, Bu-Xin, Wang, Ying, Li, Jie, Wang, Li, Fang, Yu-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10444017/
https://www.ncbi.nlm.nih.gov/pubmed/37602424
http://dx.doi.org/10.1080/13880209.2023.2244004