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Generation and purification of ACTH-secreting hPSC-derived pituitary cells for effective transplantation
Pituitary organoids are promising graft sources for transplantation in treatment of hypopituitarism. Building on development of self-organizing culture to generate pituitary-hypothalamic organoids (PHOs) using human pluripotent stem cells (hPSCs), we established techniques to generate PHOs using fee...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10444568/ https://www.ncbi.nlm.nih.gov/pubmed/37295423 http://dx.doi.org/10.1016/j.stemcr.2023.05.002 |