Generation and purification of ACTH-secreting hPSC-derived pituitary cells for effective transplantation

Pituitary organoids are promising graft sources for transplantation in treatment of hypopituitarism. Building on development of self-organizing culture to generate pituitary-hypothalamic organoids (PHOs) using human pluripotent stem cells (hPSCs), we established techniques to generate PHOs using fee...

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Detalles Bibliográficos
Autores principales: Taga, Shiori, Suga, Hidetaka, Nakano, Tokushige, Kuwahara, Atsushi, Inoshita, Naoko, Kodani, Yu, Nagasaki, Hiroshi, Sato, Yoshitaka, Tsumura, Yusuke, Sakakibara, Mayu, Soen, Mika, Miwata, Tsutomu, Ozaki, Hajime, Kano, Mayuko, Watari, Kenji, Ikeda, Atsushi, Yamanaka, Mitsugu, Takahashi, Yasuhiko, Kitamoto, Sachiko, Kawaguchi, Yohei, Miyata, Takashi, Kobayashi, Tomoko, Sugiyama, Mariko, Onoue, Takeshi, Yasuda, Yoshinori, Hagiwara, Daisuke, Iwama, Shintaro, Tomigahara, Yoshitaka, Kimura, Toru, Arima, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10444568/
https://www.ncbi.nlm.nih.gov/pubmed/37295423
http://dx.doi.org/10.1016/j.stemcr.2023.05.002

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