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Transcriptomic differences between human 8-cell-like cells reprogrammed with different methods

Embryonic genome activation (EGA) is a critical step in embryonic development. However, while EGA has been studied in mice using mouse 2-cell-like cells, human EGA remains incompletely elucidated due to the lack of an in vitro cell model recapitulating the early blastomere stage in humans. Recently,...

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Detalles Bibliográficos
Autores principales: Yoshihara, Masahito, Kere, Juha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10444576/
https://www.ncbi.nlm.nih.gov/pubmed/37478859
http://dx.doi.org/10.1016/j.stemcr.2023.06.009