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A defined roadmap of radial glia and astrocyte differentiation from human pluripotent stem cells

Human gliogenesis remains poorly understood, and derivation of astrocytes from human pluripotent stem cells (hPSCs) is inefficient and cumbersome. Here, we report controlled glial differentiation from hPSCs that bypasses neurogenesis, which otherwise precedes astrogliogenesis during brain developmen...

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Detalles Bibliográficos
Autores principales: Jovanovic, Vukasin M., Weber, Claire, Slamecka, Jaroslav, Ryu, Seungmi, Chu, Pei-Hsuan, Sen, Chaitali, Inman, Jason, De Sousa, Juliana Ferreira, Barnaeva, Elena, Hirst, Marissa, Galbraith, David, Ormanoglu, Pinar, Jethmalani, Yogita, Mercado, Jennifer Colon, Michael, Sam, Ward, Michael E., Simeonov, Anton, Voss, Ty C., Tristan, Carlos A., Singeç, Ilyas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10444578/
https://www.ncbi.nlm.nih.gov/pubmed/37451260
http://dx.doi.org/10.1016/j.stemcr.2023.06.007