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A defined roadmap of radial glia and astrocyte differentiation from human pluripotent stem cells
Human gliogenesis remains poorly understood, and derivation of astrocytes from human pluripotent stem cells (hPSCs) is inefficient and cumbersome. Here, we report controlled glial differentiation from hPSCs that bypasses neurogenesis, which otherwise precedes astrogliogenesis during brain developmen...
Autores principales: | Jovanovic, Vukasin M., Weber, Claire, Slamecka, Jaroslav, Ryu, Seungmi, Chu, Pei-Hsuan, Sen, Chaitali, Inman, Jason, De Sousa, Juliana Ferreira, Barnaeva, Elena, Hirst, Marissa, Galbraith, David, Ormanoglu, Pinar, Jethmalani, Yogita, Mercado, Jennifer Colon, Michael, Sam, Ward, Michael E., Simeonov, Anton, Voss, Ty C., Tristan, Carlos A., Singeç, Ilyas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10444578/ https://www.ncbi.nlm.nih.gov/pubmed/37451260 http://dx.doi.org/10.1016/j.stemcr.2023.06.007 |
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