Optimizing high-throughput viral vector characterization with density gradient equilibrium analytical ultracentrifugation

Viral vector-based gene therapies and vaccines require accurate characterization of capsid species. The current gold standard for assessing capsid loading of adeno-associated virus (AAV) is sedimentation velocity analytical ultracentrifugation (SV-AUC). However, routine SV-AUC analysis is often size...

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Detalles Bibliográficos
Autores principales: Sternisha, Shawn M., Wilson, Abraham D., Bouda, Emilie, Bhattacharya, Akash, VerHeul, Ross
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10444642/
https://www.ncbi.nlm.nih.gov/pubmed/37130969
http://dx.doi.org/10.1007/s00249-023-01654-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10444642/
https://www.ncbi.nlm.nih.gov/pubmed/37130969
http://dx.doi.org/10.1007/s00249-023-01654-z

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