Smooth muscle liver kinase B1 inhibits foam cell formation and atherosclerosis via direct phosphorylation and activation of SIRT6

Foam cell formation is a hallmark of the early phase of atherosclerosis. Growing evidence has demonstrated that vascular smooth muscle cells (VSMCs) comprise a considerable proportion of foam cells. Liver kinase B1 (LKB1) plays a crucial part in cardiovascular diseases. However, the role of LKB1 in...

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Detalles Bibliográficos
Autores principales: Deng, Qiming, Li, Hongxuan, Yue, Xiaolin, Guo, Chenghu, Sun, Yuanyuan, Ma, Chang, Gao, Jiangang, Wu, Yue, Du, Bin, Yang, Jianmin, Zhang, Cheng, Zhang, Wencheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10444762/
https://www.ncbi.nlm.nih.gov/pubmed/37607939
http://dx.doi.org/10.1038/s41419-023-06054-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10444762/
https://www.ncbi.nlm.nih.gov/pubmed/37607939
http://dx.doi.org/10.1038/s41419-023-06054-x

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