Demethylase-independent roles of LSD1 in regulating enhancers and cell fate transition

The major enhancer regulator lysine-specific histone demethylase 1A (LSD1) is required for mammalian embryogenesis and is implicated in human congenital diseases and multiple types of cancer; however, the underlying mechanisms remain enigmatic. Here, we dissect the role of LSD1 and its demethylase a...

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Detalles Bibliográficos
Autores principales: Zeng, Cheng, Chen, Jiwei, Cooke, Emmalee W., Subuddhi, Arijita, Roodman, Eliana T., Chen, Fei Xavier, Cao, Kaixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10444793/
https://www.ncbi.nlm.nih.gov/pubmed/37607921
http://dx.doi.org/10.1038/s41467-023-40606-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10444793/
https://www.ncbi.nlm.nih.gov/pubmed/37607921
http://dx.doi.org/10.1038/s41467-023-40606-1

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