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Histone H3 serine-57 is a CHK1 substrate whose phosphorylation affects DNA repair

Histone post-translational modifications promote a chromatin environment that controls transcription, DNA replication and repair, but surprisingly few phosphorylations have been documented. We report the discovery of histone H3 serine-57 phosphorylation (H3S57ph) and show that it is implicated in di...

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Detalles Bibliográficos
Autores principales: Parisis, Nikolaos, Dans, Pablo D., Jbara, Muhammad, Singh, Balveer, Schausi-Tiffoche, Diane, Molina-Serrano, Diego, Brun-Heath, Isabelle, Hendrychová, Denisa, Maity, Suman Kumar, Buitrago, Diana, Lema, Rafael, Nait Achour, Thiziri, Giunta, Simona, Girardot, Michael, Talarek, Nicolas, Rofidal, Valérie, Danezi, Katerina, Coudreuse, Damien, Prioleau, Marie-Noëlle, Feil, Robert, Orozco, Modesto, Brik, Ashraf, Wu, Pei-Yun Jenny, Krasinska, Liliana, Fisher, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10444856/
https://www.ncbi.nlm.nih.gov/pubmed/37607906
http://dx.doi.org/10.1038/s41467-023-40843-4