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Enhancing cryo-EM maps with 3D deep generative networks for assisting protein structure modeling

MOTIVATION: The tertiary structures of an increasing number of biological macromolecules have been determined using cryo-electron microscopy (cryo-EM). However, there are still many cases where the resolution is not high enough to model the molecular structures with standard computational tools. If...

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Detalles Bibliográficos
Autores principales: Maddhuri Venkata Subramaniya, Sai Raghavendra, Terashi, Genki, Kihara, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10444963/
https://www.ncbi.nlm.nih.gov/pubmed/37549063
http://dx.doi.org/10.1093/bioinformatics/btad494