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In utero ethanol exposure induces mitochondrial DNA damage and inhibits mtDNA repair in developing brain

INTRODUCTION: Mitochondrial dysfunction is postulated to be a central event in fetal alcohol spectrum disorders (FASD). People with the most severe form of FASD, fetal alcohol syndrome (FAS) are estimated to live only 34 years (95% confidence interval, 31 to 37 years), and adults who were born with...

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Detalles Bibliográficos
Autores principales: Darbinian, Nune, Darbinyan, Armine, Merabova, Nana, Kassem, Myrna, Tatevosian, Gabriel, Amini, Shohreh, Goetzl, Laura, Selzer, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10444992/
https://www.ncbi.nlm.nih.gov/pubmed/37621718
http://dx.doi.org/10.3389/fnins.2023.1214958