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Megakaryocyte NLRP3 hyperactivation induces mild anemia and potentiates inflammatory response in mice
BACKGROUND: The NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inflammasome has been described in both immune cells and platelets, but its role in the megakaryocyte (MK) lineage remains elusive. OBJECTIVE: The aim of this study was to explore the role of NLRP3 inflammasome in megakaryocyt...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445124/ https://www.ncbi.nlm.nih.gov/pubmed/37622117 http://dx.doi.org/10.3389/fimmu.2023.1226196 |